Thanks for great configuration. I have made some additional changes after installing with this script:

Rise of the Ages is a mod for Rise of Nations: Extrended Edition, created by 0wcabibi88. Description: This mod completely overhauls the game. Each age now feels more extended and isn't rushed, as well as gameplay is more strategic than just spamming units from production facilities. Rise of Nations is an historical real-time strategy (RTS) game which combines the epic scope of traditional turn-based strategy (TBS) games with the fast-paced. Rise of Nations Update for Mac. The rise of Nations: Thrones and Patriots is the official expansion pack to the real-time strategy video game Rise of Nations. The game is the second in a series of Rising of Nations games by Big Huge Games.

If your your mouse is not working inside game configuration (like mine) and you still want to play solo, I have uploaded default .dat file in with 8 players (tougher), surrvival of the fittest, random land map, no wonder victory etc.

You need to put it in your play on linux virtual drive: drive_c/users/mat/Application Data/Microsoft Games/Rise of Nations/ and rename .dat file to $YourRoNProfileName.dat

You can change any configuration inside it in any editor if you want.

Another thing that I had issues with is Fullcreen on Ubuntu 16.04 (Unity)

For Fullscreen game, next requirements are needed:

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On your playonlinux virtual drive, you need to change rise.ini or rise2.ini (if you play Thrones and Patriots) in your Rise of Nations folder.

You need to set these parameters:

Windowed Width=1366
Windowed Height=768
FullScreen=1

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You need to set width and height to size of your resolution.

Next thing is wine configuration on RoN virtual drive. In graphics tab, you only need to set Automatically capture the mouse in full-screen windows and disable all other checkboxes like in picture:

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And that's it! Happy gaming :)